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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LRRC9 All Species: 4.24
Human Site: S289 Identified Species: 9.33
UniProt: Q6ZRR7 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.4
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZRR7 NP_008949 1453 166911 S289 E E R V K L F S F V K K T L E
Chimpanzee Pan troglodytes XP_509984 1111 128143 Q64 T S L T I V A Q D I K E I S G
Rhesus Macaque Macaca mulatta XP_001095204 2201 254670 K305 E E I K N Q D K L N K S L K E
Dog Lupus familis XP_547839 1687 192379 S391 E E R I K L F S F V K K N L E
Cat Felis silvestris
Mouse Mus musculus Q8CDN9 1456 167284 R284 L Q K L P E E R I K L F N F A
Rat Rattus norvegicus XP_001077512 1460 168063 R284 L Q K L P E E R I K L F N F A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517101 1373 156827 L249 L P E D Q I K L F T F S I R N
Chicken Gallus gallus XP_415403 2346 270651 L516 H Q L Q E G A L A L E K Q M E
Frog Xenopus laevis Q6NRC9 1030 118723
Zebra Danio Brachydanio rerio NP_001107274 984 113434
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784143 1493 168392 R299 K E K R S L T R G T K D R L K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 75.5 20.2 72.6 N.A. 80.6 80.8 N.A. 60.5 20.3 20.3 33.5 N.A. N.A. N.A. N.A. 44.6
Protein Similarity: 100 75.9 36.4 78.5 N.A. 88.8 89.1 N.A. 73.4 35.1 38.3 46.5 N.A. N.A. N.A. N.A. 64.5
P-Site Identity: 100 6.6 26.6 86.6 N.A. 0 0 N.A. 6.6 13.3 0 0 N.A. N.A. N.A. N.A. 26.6
P-Site Similarity: 100 26.6 26.6 93.3 N.A. 20 20 N.A. 20 46.6 0 0 N.A. N.A. N.A. N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 19 0 10 0 0 0 0 0 19 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 0 0 10 0 10 0 0 10 0 0 0 % D
% Glu: 28 37 10 0 10 19 19 0 0 0 10 10 0 0 37 % E
% Phe: 0 0 0 0 0 0 19 0 28 0 10 19 0 19 0 % F
% Gly: 0 0 0 0 0 10 0 0 10 0 0 0 0 0 10 % G
% His: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 10 10 10 10 0 0 19 10 0 0 19 0 0 % I
% Lys: 10 0 28 10 19 0 10 10 0 19 46 28 0 10 10 % K
% Leu: 28 0 19 19 0 28 0 19 10 10 19 0 10 28 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % M
% Asn: 0 0 0 0 10 0 0 0 0 10 0 0 28 0 10 % N
% Pro: 0 10 0 0 19 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 28 0 10 10 10 0 10 0 0 0 0 10 0 0 % Q
% Arg: 0 0 19 10 0 0 0 28 0 0 0 0 10 10 0 % R
% Ser: 0 10 0 0 10 0 0 19 0 0 0 19 0 10 0 % S
% Thr: 10 0 0 10 0 0 10 0 0 19 0 0 10 0 0 % T
% Val: 0 0 0 10 0 10 0 0 0 19 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _